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Drug Abuse 101 - What You Absolutely Need to Know
from:by Ronit khera
IntroductionDue to the change in world’s social and economic pattern with so much of stressors and so less time for each other and even for oneself to get relaxed, there is a hug scope for the immature population to go for unnatural and short-lived pleasures which although might pose severe threat to one’s own health and well being and even to life. Hence late teenagers and people in early twenties are those who are most prone to it as they both have reason and accessibility for the same.DefinitionsDrug abuse refers to self or peer medication of a drug in any amount or in any manner that cannot be medically or socially justified for its use.Drug addiction means the compulsive use of a drug, procuring it to take precedence over other activities.Drug habituation means less intense craving of the drug.Problem statementAccording to NIDA (national institute on drug abuse) the Monitoring the Future survey that is studying the trends since many years shows that there has been significantly decreased consumption of all the types of drugs except the inhalants. Although there has been decreasing trends but they are not at all satisfying as there are still a large number of teenagers specially the 8th graders who tend to get involved into this.The problem with these types of drug is both direct and indirect. The direct effect of these drugs is for e.g. addiction, insomnia, hyper somnolence, increased reaction time and so on and so forth. But the indirect ones are equally dangerous for e.g. easy prey to AIDS, Hepatitis B & C and other infectious diseases.Cause of the problem, why abuse?The root cause of the problem are manifold but the main causes are the teenagers with a history of drug abuse in the family, single parent family, economically or socially deprived children and surprisingly teenagers of Hispanic origin.TypesThere are many different types of drug abuse. These have traditionally been divided based on the action on the brain, chemical salt or the purpose for which it is used medically or socially. Some of these are:a) Nicotine used in cigaretteOne of most heavily used and the most damaging of the drugs. It damages not only the lungs and immunity but also the whole body. Known to be implicated in the causation on lung, ovarian, skin and certain other cancers.b) CocaineKnown to have damaging effects on cardiovascular and cerebrovascular systems.c) LSDCauses hypertension, tachycardia and insomnia. Also disturbs the control of body temperature.d) MarijuanaHas caused memory and learning disabilities.e) MethamphetamineInsomnia, anorexia, hyperactivity and psychosis are its major side effects.f) Pain medicationsCan lead to dependence and drug craving.g) Club drugs & date rape drugsCauses decreased muscle power and amnesia.h) SteroidsIn males causes certain feminine changes and vice versa in males besides causes overall retarded development.Diagnosing drug abuseAlthough the diagnosis of the abuse is not difficult at a full-blown stage but the important features at an early stage are the teenager becoming less social, poor performance at school, anorexia, unusual sleep pattern and weakness.
Problem solvingThe main success lies in convincing the patient two things: first that the drug is not helping him or her in any way and secondly the drug abuse can be given up in a joint effort. Obviously that means managing the drug abuse needs both medical and social treatment.
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Press Release
Pfizer announced today that the Committee for Human Medicinal Products (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion regarding the marketing authorization of axitinib in the European Union (EU), for the treatment of adult patients with advanced renal cell carcinoma (RCC), a type of advanced kidney cancer, after failure of prior treatment with sunitinib or a cytokine.
Read more...Pfizer Provides Topline Results From Phase 3 Study Of Torisel® As Second-Line Treatment In Advanced Renal Cell ...
Pfizer Inc announced today that the Phase 3 INTORSECT study, evaluating TORISEL® in patients with advanced renal cell carcinoma whose disease had progressed on or after SUTENT® therapy, did not meet the primary endpoint of prolonging progression free survival when compared to sorafenib.
Read more...Pfizer says EU recommends approval of Inlyta
Pfizer Inc. said Friday that European Union regulators are recommending approval for its kidney cancer drug Inlyta.A European Union advisory committee recommended that Inlyta be approved as a treatment ...
Read more...Pfizer’s Axitinib Receives Positive Opinion from the Committee for Human Medicinal Products for the Second-line ...
NEW YORK--(BUSINESS WIRE)--Pfizer announced today that the Committee for Human Medicinal Products (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion regarding the marketing authorization of axitinib in the European Union (EU), for the treatment of adult patients with advanced renal cell carcinoma (RCC), a type of advanced kidney cancer, after failure of prior treatment ...
Read more...Targeted Therapies Drive the Global Renal Cell Carcinoma (RCC) Drugs Market, According to New Report by Global ...
GIA announces the release of a comprehensive global report on the Kidney Cancer Drugs markets. The global market for Renal Cell Carcinoma (RCC) Drugs is forecast to reach $3.03 billion by the year 2017, driven by the growing preference for targeted therapies in the treatment of RCC. Additionally, growth is also expected to stem from the introduction of new emerging therapies, increased use of ...
Read more...Pfizers Axitinib Receives Positive Opinion from the Committee for Human Medicinal Products for the Second-line ...
Pfizer announced today that the Committee for Human Medicinal Products ...
Read more...Aveo sees positive safety data for kidney cancer drug
Aveo Oncology (NASDAQ:AVEO) of Cambridge and partner Astellas Pharma Inc. (TSE:4503) of Tokyo revealed more data from the TIVO-1 Phase 3 clinical trial of tivozanib, their drug candidate for renal cell carcinoma, including positive tolerability data.
Read more...Disappointing Data on Pfizer Drug
Results from the phase III INTORSECT study showed that Torisel failed to achieve the primary endpoint of progression free survival.
Read more...Aveo kidney cancer drug more tolerated than Nexavar
(Reuters) - Patients taking a kidney cancer drug being developed by Aveo Pharmaceuticals Inc were half as likely to need a break from the medication due to side effects than those on the widely used medicine Nexavar, according to data released on Wednesday. There were also significantly fewer patients taking Aveo's tivozanib who required a dose reduction than those on Nexavar. ...
Read more...Novartis Drug Afinitor® Approved By FDA As First Medication To Treat Patients With Non-Cancerous Kidney Tumors ...
Novartis Pharmaceuticals Corporation ("Novartis") announced today that the US Food and Drug Administration (FDA) approved Afinitor® (everolimus) tablets* for the treatment of adult patients with kidney tumors known as renal angiomyolipomas and tuberous sclerosis complex (TSC), who do not require immediate surgery(2).
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